Cystic Fibrosis Research Institute

Over 30,000 in the USA live with a disease that has no cure Help us find one DONATE > Life with CF is a physical and emotional roller coaster CF Quality of Life program offers needed support SUPPORT PROGRAMS > CF can be isolating: You are not alone in your daily fight Meet others at CFRI's CF Summer Retreat   COMMUNITY EVENTS > Cystic Fibrosis still has no cure CF research is the answer RESEARCH > Did you know CF is the most common fatal genetic disease in the U.S.? And the median age of death is 30 years? KNOW MORE > CF & COVID-19 CFRI recommends that individuals with CF and their families and friends utilize extra precautionary measures READ MORE >


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To be a global resource for the cystic fibrosis community while pursuing a cure through research, education, advocacy, and support.



CFRI is a nonprofit organization that funds innovative CF research and offers education, advocacy and psychosocial support programs to those affected by CF.

Vision Statement

To find a cure for cystic fibrosis while enhancing quality of life for the CF community.


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Cystic fibrosis (CF) is a rare genetic, chronic, progressive disease that affects over 30,000 people in the United States, and over 70,000 people worldwide. While most people associate cystic fibrosis with progressive lung disease, CF impacts the respiratory, digestive, reproductive, and endocrine systems. Once considered a childhood disease, over half of those living with CF in the United States are over the age of 18. While life expectancy for those recently diagnosed has reached the mid-forties, the median age of death remains only thirty years. Progress in research has led to new therapies that can extend and enhance the lives of those with CF, but there is still no cure.


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CFRI Community Newsletter

For the fourth consecutive year, CFRI received 4 stars from Charity Navigator, and is recognized as a top-rated charity by Great Nonprofits

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Charity Navigator - Four Star Charity